Endocrine Abstracts

Background and aims: Interleukin-12 (IL-12) is a pro inflammatory cytokine, which was suggested to play a key role in the pathogenesis of Th1-cell-mediated autoimmune diseases. The aim of our study was to estimate the association of 1188A/C polymorphism of IL12B gene with the predisposition to Graves’ disease (GD) in Polish population.Materials and methods: The study was performed in the group consisting of 245 individuals with GD sequentially recru...